MusculoskeletalICD-10: G57.6Fairly common, particularly in middle-aged women

Morton's Neuroma

Also known as: Interdigital neuroma, Intermetatarsal neuroma, Morton's metatarsalgia

Morton's neuroma is a painful thickening of the tissue around one of the nerves leading to your toes, most often between the third and fourth toes. Despite the name, it is not a true tumour but an irritated, swollen nerve that is being squeezed between the long bones of the foot. The classic description is feeling as though you are standing on a pebble or a bunched-up sock, with burning pain in the ball of the foot that shoots into the toes and sometimes numbness or tingling. It is far more common in women, largely because of narrow or high-heeled shoes, and in runners and people who spend long hours on their feet. Most cases improve with footwear changes and padding; injections or surgery are reserved for persistent pain.

At a Glance

Common symptoms
Burning, sharp or aching pain in the ball of the foot that may radiate into the toes, A sensation of standing on a pebble or a fold in your sock, Tingling or numbness in the affected toes
Main treatments
Switching to wide, low-heeled shoes with a soft sole and roomy toe box, Metatarsal pads or custom orthotics placed just behind the ball of the foot to spread the bones and relieve pressure on the nerve, Reducing high-impact activity temporarily and switching to swimming or cycling
Category
Musculoskeletal · Fairly common, particularly in middle-aged women
See a doctor if
Forefoot pain or toe tingling lasting more than a few days despite changing shoes

Symptoms

Burning, sharp or aching pain in the ball of the foot that may radiate into the toes
A sensation of standing on a pebble or a fold in your sock
Tingling or numbness in the affected toes
Pain that worsens with walking, running or wearing tight shoes and eases when you remove the shoe and rub the foot
A clicking feeling when walking (Mulder's click)
Usually no visible lump on the outside of the foot

Causes

  • Compression and irritation of the nerve between the metatarsal heads
  • Narrow, tight or pointed shoes that squeeze the toes together
  • High heels, which shift body weight onto the forefoot
  • High-impact activities such as running, court sports or dancing
  • Foot deformities such as bunions, hammer toes, flat feet or high arches that alter forefoot mechanics
  • Injury to the forefoot

Risk Factors

  • Being female, with onset typically between 30 and 60
  • Regularly wearing high heels or narrow shoes
  • Running and high-impact sports
  • Bunions, hammer toes, flat feet or high arches
  • Jobs involving long periods standing or walking on hard surfaces

Diagnosis

  • Physical examination that reproduces the pain by pressing on the space between the toes or squeezing the forefoot
  • Checking for a click (Mulder's sign) when the metatarsals are compressed
  • Ultrasound, which can show the thickened nerve and exclude other causes
  • MRI in unclear cases or before surgery
  • X-rays to rule out stress fractures or arthritis

Treatment

  • Switching to wide, low-heeled shoes with a soft sole and roomy toe box
  • Metatarsal pads or custom orthotics placed just behind the ball of the foot to spread the bones and relieve pressure on the nerve
  • Reducing high-impact activity temporarily and switching to swimming or cycling
  • Anti-inflammatory medication and icing the foot after activity
  • Corticosteroid injection around the nerve for persistent pain
  • Surgery to release the surrounding ligament or remove the neuroma if conservative treatment fails, which usually relieves pain but can leave permanent numbness between the toes
  • Supportive: foot and calf stretches and massage to ease tightness that increases forefoot loading

Prevention

  • Wear shoes with a wide toe box and a heel of 2.5 centimetres or less
  • Avoid narrow, pointed or tight shoes, especially for long periods
  • Use cushioned insoles or metatarsal pads if you stand a lot or play high-impact sports
  • Maintain a healthy body weight to reduce forefoot pressure
  • Rest the feet after intense activity and address any foot pain early

When to See a Doctor

  • Forefoot pain or toe tingling lasting more than a few days despite changing shoes
  • Pain that limits walking, exercise or work
  • Numbness in the toes that is persistent
  • Pain after a foot injury, as a fracture may need to be excluded
  • Swelling, redness or warmth in the forefoot

Frequently Asked Questions

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