PediatricICD-10: B08.20Very common; nearly all children have been infected by age 2, though many have no obvious symptoms

Roseola

Also known as: Roseola infantum, Sixth disease, Exanthem subitum

Roseola is a common, mild viral infection that mainly affects babies and toddlers between six months and two years of age. It is caused by human herpesvirus 6 (and sometimes 7) and follows a distinctive pattern: a sudden high fever lasting three to five days, after which the fever drops abruptly and a rash of small pink spots appears on the trunk, spreading to the neck, face, and limbs. The rash is not itchy and fades within a day or two. Because the fever can be high, roseola is one of the more common triggers of febrile seizures in young children, which is alarming but almost always harmless. Most children recover completely without treatment and are immune afterwards.

At a Glance

Common symptoms
A sudden high fever, often 39.5°C or above, lasting 3 to 5 days, A child who seems relatively well and active despite the fever, Mild runny nose, sore throat, cough, or swollen glands in the neck
Main treatments
No specific treatment is needed; roseola resolves on its own, Paracetamol or ibuprofen to make a feverish child more comfortable (following age-appropriate dosing), Plenty of fluids: breast milk, formula, water, or diluted juice depending on age
Category
Pediatric · Very common; nearly all children have been infected by age 2, though many have no obvious symptoms
See a doctor if
Fever above 39.5°C that does not come down with medication, or any fever in a baby under 3 months

Symptoms

A sudden high fever, often 39.5°C or above, lasting 3 to 5 days
A child who seems relatively well and active despite the fever
Mild runny nose, sore throat, cough, or swollen glands in the neck
A rash of small pink or red spots appearing as the fever ends, starting on the chest and back
Rash that spreads to the neck, face, arms, and legs and is not itchy
Irritability, mild diarrhoea, or reduced appetite
Swollen eyelids or puffiness around the eyes in some children

Causes

  • Infection with human herpesvirus 6 (HHV-6), and less often HHV-7
  • Spread through saliva and respiratory droplets, often from adults or older children who carry the virus without symptoms
  • Close contact and shared cups, toys, or cutlery
  • Waning of protective antibodies passed from the mother, which leaves babies susceptible after about 6 months

Risk Factors

  • Age 6 months to 2 years, when protection from maternal antibodies has waned
  • Attendance at nursery or daycare
  • Older siblings
  • Weakened immune system, where the virus can cause more serious illness

Diagnosis

  • Clinical diagnosis based on the typical sequence of high fever followed by a rash
  • Examination to rule out other causes of fever, such as ear or urinary infection, during the fever phase
  • Blood tests only in unusual or severe cases, or in children with weakened immunity

Treatment

  • No specific treatment is needed; roseola resolves on its own
  • Paracetamol or ibuprofen to make a feverish child more comfortable (following age-appropriate dosing)
  • Plenty of fluids: breast milk, formula, water, or diluted juice depending on age
  • Light clothing and a comfortably cool room; avoid cold baths or sponging
  • Antiviral medication only in rare cases for children with severely weakened immune systems
  • Supportive: rest, cuddles, and keeping the child home until the fever has gone

Prevention

  • Regular hand washing for everyone caring for the child
  • Avoid sharing cups, spoons, and dummies between children
  • Clean toys and surfaces regularly in nurseries
  • There is no vaccine; nearly all children are exposed by early childhood and become immune

When to See a Doctor

  • Fever above 39.5°C that does not come down with medication, or any fever in a baby under 3 months
  • A seizure (call emergency services if it lasts more than 5 minutes)
  • Fever lasting more than 5 days, or a rash that does not fade when pressed with a glass
  • Drowsiness, difficulty waking, a stiff neck, or refusal to drink
  • Your child has a weakened immune system and develops a high fever

Frequently Asked Questions

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