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InfectiousICD-10: B02About 1 in 3 people in the US will develop shingles in their lifetime

Shingles

Also known as: Herpes zoster

Shingles is a viral infection caused by the reactivation of the varicella-zoster virus, the same virus that causes chickenpox. It produces a painful, blistering rash that typically appears as a stripe of blisters on one side of the body or face. Shingles is most common in older adults and people with weakened immune systems, and vaccination can significantly reduce the risk.

Symptoms

Pain, burning, or tingling sensation on one side of the body
Red rash that appears a few days after the pain
Fluid-filled blisters that break open and crust over
Itching at the rash site
Fever and chills
Headache
Fatigue
Sensitivity to touch in the affected area

Causes

  • Reactivation of the dormant varicella-zoster virus in nerve tissue
  • Weakened immune system allowing viral reactivation
  • Age-related decline in immune function

Risk Factors

  • Age over 50 years
  • Previous chickenpox infection
  • Immunosuppressive medications or conditions
  • Chronic stress or illness
  • Cancer treatments such as chemotherapy or radiation

Diagnosis

  • Clinical examination of the characteristic rash pattern
  • PCR testing of blister fluid or skin scrapings
  • Direct fluorescent antibody testing
  • Viral culture in atypical cases

Treatment

  • Antiviral medications such as acyclovir, valacyclovir, or famciclovir started within 72 hours
  • Pain relief with over-the-counter or prescription analgesics
  • Topical capsaicin or lidocaine patches for postherpetic neuralgia
  • Corticosteroids to reduce inflammation in some cases
  • Cool compresses to soothe blisters

Prevention

  • Shingrix vaccine recommended for adults 50 and older
  • Vaccination for immunocompromised adults as advised by their doctor
  • Avoiding contact with people who have not had chickenpox while blisters are active

When to See a Doctor

  • Pain or rash near the eye, which can lead to vision loss
  • Widespread rash suggesting a weakened immune system
  • Rash that does not improve within 10 days
  • Severe pain that disrupts daily activities

Frequently Asked Questions

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Medical Disclaimer: This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider.

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