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InfectiousICD-10: A49.0Staph bacteria colonize about 30% of the population; invasive MRSA infects about 80,000 Americans annually

Staphylococcal Infection

Also known as: Staph infection, MRSA, Staphylococcus aureus infection

Staphylococcal infections are caused by Staphylococcus bacteria, commonly found on the skin and in the nose, which can cause a range of illnesses from minor skin infections to life-threatening conditions like bloodstream infections. Methicillin-resistant Staphylococcus aureus (MRSA) is a particularly concerning strain that is resistant to many common antibiotics. Prompt treatment and proper hygiene are essential for managing these infections.

Symptoms

Red, swollen, and painful skin boils or abscesses
Warm area of skin that is tender to touch
Pus or drainage from a wound
Fever
Skin rash that resembles a spider bite
Cellulitis causing red, swollen skin
In severe cases, symptoms of bloodstream infection including high fever and low blood pressure

Causes

  • Infection by Staphylococcus aureus bacteria
  • Bacteria entering through cuts, scrapes, or surgical wounds
  • Skin-to-skin contact with an infected person
  • Contact with contaminated surfaces or objects

Risk Factors

  • Open wounds or surgical incisions
  • Weakened immune system
  • Hospital stays or healthcare facility exposure
  • Use of invasive medical devices such as catheters
  • Close contact in settings like gyms, locker rooms, or military barracks
  • Chronic skin conditions such as eczema

Diagnosis

  • Wound culture to identify the specific bacteria
  • Blood cultures for suspected bloodstream infections
  • Antibiotic sensitivity testing to guide treatment
  • Imaging studies if deep tissue infection is suspected

Treatment

  • Drainage of abscesses
  • Antibiotics appropriate for the strain, including MRSA-specific options
  • Wound care and dressing changes
  • Intravenous antibiotics for severe or invasive infections
  • Decolonization protocols with mupirocin and chlorhexidine washes

Prevention

  • Regular handwashing with soap and water
  • Keeping wounds clean and covered until healed
  • Not sharing personal items like towels or razors
  • Cleaning and disinfecting frequently touched surfaces

When to See a Doctor

  • Skin infection that is red, swollen, and warm with increasing pain
  • Fever accompanying a skin wound or infection
  • Infection that does not improve with initial antibiotic treatment
  • Recurrent skin infections

Frequently Asked Questions

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