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InfectiousICD-10: A37About 15,000-40,000 cases reported annually in the US, with actual numbers likely higher

Whooping Cough

Also known as: Pertussis

Whooping cough is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis, characterized by severe coughing fits that can end with a high-pitched whooping sound. It is most dangerous in infants who are too young to be vaccinated and can cause life-threatening complications. Vaccination with DTaP and Tdap is the most effective way to prevent pertussis.

Symptoms

Initial cold-like symptoms with mild cough and runny nose
Severe, uncontrollable coughing fits lasting one to two minutes
Whooping sound when breathing in after a coughing fit
Vomiting after coughing episodes
Exhaustion after coughing fits
Face turning red or blue during coughing
Apnea (breathing pauses) in infants

Causes

  • Infection with Bordetella pertussis bacteria
  • Spread through respiratory droplets from coughing or sneezing
  • Close contact with an infected person

Risk Factors

  • Infants under 12 months who are not fully vaccinated
  • Waning vaccine immunity in adolescents and adults
  • Close contact with an infected individual
  • Incomplete vaccination series

Diagnosis

  • Nasopharyngeal swab for culture or PCR testing
  • Blood tests showing elevated white blood cell count
  • Clinical evaluation based on characteristic cough
  • Chest X-ray to check for complications

Treatment

  • Antibiotics such as azithromycin, clarithromycin, or erythromycin
  • Early treatment to reduce severity and contagiousness
  • Hospitalization for infants with severe disease
  • Supportive care including fluids, suctioning, and oxygen
  • Prophylactic antibiotics for close contacts

Prevention

  • DTaP vaccine series for children in five doses
  • Tdap booster for adolescents and adults
  • Tdap vaccination during each pregnancy to protect newborns
  • Post-exposure prophylaxis with antibiotics for close contacts

When to See a Doctor

  • Persistent cough, especially with a whooping sound
  • Coughing fits that cause vomiting or turning red or blue
  • Any coughing illness in an infant
  • Known exposure to whooping cough

Frequently Asked Questions

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Medical Disclaimer: This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider.

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