Dry Mouth (Xerostomia)
Also known as: Xerostomia, Cottonmouth
Dry mouth, known medically as xerostomia, is the feeling of insufficient saliva in the mouth. Saliva does far more than keep the mouth comfortable — it neutralizes acids, washes away food, fights bacteria, and helps with chewing, swallowing, and taste. When salivary flow drops, the result can be difficulty eating and speaking, bad breath, and a sharply increased risk of tooth decay and oral infections. Dry mouth is most often a side effect of medications, but it can also stem from medical conditions, dehydration, or cancer treatment.
Symptoms
Causes
- Medication side effects (antihistamines, antidepressants, blood pressure drugs, and many others)
- Dehydration
- Autoimmune conditions such as Sjögren's syndrome
- Radiation therapy to the head and neck
- Chemotherapy
- Nerve damage, diabetes, and certain infections
- Mouth breathing, smoking, and alcohol use
Risk Factors
- Older age (largely because of increased medication use)
- Taking multiple medications
- Cancer treatment involving the head and neck
- Autoimmune disease
- Uncontrolled diabetes
- Tobacco and alcohol use
Diagnosis
- Review of symptoms, medical history, and medications
- Examination of the mouth and measurement of saliva flow
- Blood tests if an autoimmune or systemic cause is suspected
- Imaging or biopsy of salivary glands in selected cases
- Testing for Sjögren's syndrome when indicated
Treatment
- Reviewing and adjusting causative medications when possible
- Saliva substitutes and oral moisturizing gels or sprays
- Prescription medications that stimulate saliva (pilocarpine, cevimeline)
- Sugar-free gum or lozenges to stimulate flow
- Frequent sips of water and good hydration
- Fluoride treatments and diligent dental care to prevent decay
- Treating the underlying condition (e.g., diabetes, Sjögren's)
Prevention
- Stay well hydrated throughout the day
- Avoid tobacco, alcohol, and caffeine, which are drying
- Breathe through your nose rather than your mouth
- Use a humidifier at night
- Maintain excellent oral hygiene and regular dental visits
- Discuss drying side effects with your doctor before changing medications
When to See a Doctor
- Persistent dry mouth that does not improve with hydration
- Difficulty eating, swallowing, or speaking
- Frequent mouth sores or oral infections
- Dry eyes and dry mouth together, which may suggest Sjögren's syndrome
- Increasing tooth decay despite good oral care
Frequently Asked Questions
Related Conditions
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