DigestiveICD-10: R68.2Affects an estimated 10 to 30 percent of adults, rising with age and medication use

Dry Mouth (Xerostomia)

Also known as: Xerostomia, Cottonmouth

Dry mouth, known medically as xerostomia, is the feeling of insufficient saliva in the mouth. Saliva does far more than keep the mouth comfortable — it neutralizes acids, washes away food, fights bacteria, and helps with chewing, swallowing, and taste. When salivary flow drops, the result can be difficulty eating and speaking, bad breath, and a sharply increased risk of tooth decay and oral infections. Dry mouth is most often a side effect of medications, but it can also stem from medical conditions, dehydration, or cancer treatment.

Symptoms

A dry, sticky feeling in the mouth
Thick or stringy saliva
Frequent thirst
Difficulty chewing, swallowing, or speaking
Bad breath
A dry or grooved tongue and altered sense of taste
Cracked lips and sores at the corners of the mouth
More frequent cavities and gum problems

Causes

  • Medication side effects (antihistamines, antidepressants, blood pressure drugs, and many others)
  • Dehydration
  • Autoimmune conditions such as Sjögren's syndrome
  • Radiation therapy to the head and neck
  • Chemotherapy
  • Nerve damage, diabetes, and certain infections
  • Mouth breathing, smoking, and alcohol use

Risk Factors

  • Older age (largely because of increased medication use)
  • Taking multiple medications
  • Cancer treatment involving the head and neck
  • Autoimmune disease
  • Uncontrolled diabetes
  • Tobacco and alcohol use

Diagnosis

  • Review of symptoms, medical history, and medications
  • Examination of the mouth and measurement of saliva flow
  • Blood tests if an autoimmune or systemic cause is suspected
  • Imaging or biopsy of salivary glands in selected cases
  • Testing for Sjögren's syndrome when indicated

Treatment

  • Reviewing and adjusting causative medications when possible
  • Saliva substitutes and oral moisturizing gels or sprays
  • Prescription medications that stimulate saliva (pilocarpine, cevimeline)
  • Sugar-free gum or lozenges to stimulate flow
  • Frequent sips of water and good hydration
  • Fluoride treatments and diligent dental care to prevent decay
  • Treating the underlying condition (e.g., diabetes, Sjögren's)

Prevention

  • Stay well hydrated throughout the day
  • Avoid tobacco, alcohol, and caffeine, which are drying
  • Breathe through your nose rather than your mouth
  • Use a humidifier at night
  • Maintain excellent oral hygiene and regular dental visits
  • Discuss drying side effects with your doctor before changing medications

When to See a Doctor

  • Persistent dry mouth that does not improve with hydration
  • Difficulty eating, swallowing, or speaking
  • Frequent mouth sores or oral infections
  • Dry eyes and dry mouth together, which may suggest Sjögren's syndrome
  • Increasing tooth decay despite good oral care

Frequently Asked Questions

Related Conditions

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