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DigestiveICD-10: K21.0Affects approximately 20% of the U.S. adult population

Gastroesophageal Reflux Disease (GERD)

Also known as: GERD, Acid Reflux Disease, Chronic Acid Reflux

GERD is a chronic condition in which stomach acid frequently flows back into the esophagus, irritating its lining. It occurs when the lower esophageal sphincter weakens or relaxes abnormally. Left untreated, GERD can lead to esophagitis, Barrett's esophagus, and an increased risk of esophageal cancer.

Symptoms

Burning sensation in the chest (heartburn), especially after eating
Regurgitation of food or sour liquid
Difficulty swallowing (dysphagia)
Sensation of a lump in the throat
Chronic cough, particularly at night
Laryngitis or hoarseness
Worsening of asthma symptoms
Disrupted sleep from nighttime reflux

Causes

  • Weakened or dysfunctional lower esophageal sphincter
  • Hiatal hernia allowing acid to reflux more easily
  • Delayed stomach emptying (gastroparesis)
  • Obesity increasing abdominal pressure
  • Pregnancy-related hormonal and physical changes

Risk Factors

  • Obesity or overweight
  • Pregnancy
  • Hiatal hernia
  • Smoking
  • Eating large meals or eating late at night
  • Certain foods (fatty, spicy, chocolate, caffeine, alcohol)

Diagnosis

  • Clinical diagnosis based on symptoms and response to acid-suppressing therapy
  • Upper endoscopy to evaluate for esophagitis or Barrett's esophagus
  • Ambulatory 24-hour pH monitoring
  • Esophageal manometry to assess sphincter function

Treatment

  • Lifestyle modifications (weight loss, elevating head of bed, dietary changes)
  • Proton pump inhibitors (omeprazole, esomeprazole, lansoprazole)
  • H2 receptor blockers (famotidine) for milder symptoms
  • Antacids for occasional symptom relief
  • Fundoplication surgery or LINX device for refractory cases

Prevention

  • Maintain a healthy weight
  • Avoid eating within 3 hours of bedtime
  • Elevate the head of your bed 6–8 inches
  • Avoid trigger foods and beverages
  • Quit smoking

When to See a Doctor

  • Heartburn occurs more than twice a week
  • Symptoms persist despite over-the-counter medications
  • You experience difficulty swallowing or unintentional weight loss
  • You develop chest pain (rule out cardiac causes first)

Frequently Asked Questions

Related Conditions

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Medical Disclaimer: This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider.

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