InfectiousICD-10: B97.7About 42 million Americans have HPV; nearly 80% will be infected at some point

HPV (Human Papillomavirus)

Also known as: Human Papillomavirus, Genital Warts Virus

HPV is the most common STI, with over 200 types identified. Most infections are harmless and clear on their own, but certain high-risk strains (HPV 16, 18) can cause cervical, throat, anal, and other cancers. The HPV vaccine is highly effective at preventing infection with the most dangerous strains.

At a Glance

Common symptoms
Most HPV infections cause no symptoms, Genital warts (flesh-colored bumps in the genital area), Common warts on hands or fingers
Main treatments
Most infections clear without treatment within 1–2 years, Topical treatments for warts: imiquimod, podophyllin, trichloroacetic acid, Cryotherapy or electrocautery for wart removal
Category
Infectious · About 42 million Americans have HPV; nearly 80% will be infected at some point
See a doctor if
You notice unusual bumps or growths in the genital area

Symptoms

Most HPV infections cause no symptoms
Genital warts (flesh-colored bumps in the genital area)
Common warts on hands or fingers
Plantar warts on feet
Flat warts on the face or legs
Abnormal Pap smear results

Causes

  • HPV transmitted through skin-to-skin contact, primarily sexual
  • Over 40 types can infect the genital area
  • High-risk types (HPV 16, 18) cause most HPV-related cancers
  • Low-risk types (HPV 6, 11) cause most genital warts

Risk Factors

  • Multiple sexual partners
  • Unvaccinated status
  • Weakened immune system
  • Early onset of sexual activity
  • Skin-to-skin contact with infected individuals

Diagnosis

  • Pap smear to detect cervical cell abnormalities
  • HPV DNA test to identify high-risk strains
  • Visual examination for genital warts
  • Biopsy of abnormal lesions

Treatment

  • Most infections clear without treatment within 1–2 years
  • Topical treatments for warts: imiquimod, podophyllin, trichloroacetic acid
  • Cryotherapy or electrocautery for wart removal
  • LEEP for cervical precancers
  • Regular Pap smear surveillance

Prevention

  • HPV vaccination — recommended ages 11–12, catch-up through age 26
  • Routine cervical cancer screening
  • Consistent condom use
  • Limiting number of sexual partners

When to See a Doctor

  • You notice unusual bumps or growths in the genital area
  • Your Pap smear shows abnormal results
  • You are unsure of your HPV vaccination status
  • You are over 30 and have never been screened

Frequently Asked Questions

Related Conditions

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