Substance Use Disorder
Also known as: Addiction, Drug addiction, Substance abuse
Substance use disorder is a chronic brain condition characterized by the compulsive use of substances such as alcohol, drugs, or medications despite harmful consequences. It involves changes in brain circuits related to reward, stress, and self-control that can persist long after substance use stops. Recovery is achievable through a combination of behavioral therapies, medications, and ongoing support.
Symptoms
Causes
- Changes in brain reward circuitry from repeated substance exposure
- Genetic vulnerability accounting for 40-60% of risk
- Environmental factors including peer pressure and early exposure
- Mental health conditions contributing to self-medication
- Chronic stress and trauma
Risk Factors
- Family history of addiction
- Mental health disorders such as depression, anxiety, or PTSD
- Early age of first substance use
- Lack of social support or family involvement
- Peer pressure and environmental exposure
- History of childhood trauma or adverse experiences
Diagnosis
- Clinical interview using DSM-5 criteria for severity classification
- Screening tools such as CAGE, AUDIT, or DAST questionnaires
- Urine or blood drug screening
- Assessment of co-occurring mental health disorders
Treatment
- Behavioral therapies including CBT and motivational interviewing
- Medication-assisted treatment such as methadone, buprenorphine, or naltrexone for opioid use disorder
- Medically supervised detoxification
- Residential or outpatient rehabilitation programs
- 12-step programs and peer support groups
- Treatment of co-occurring mental health conditions
Prevention
- Education about risks of substance use, especially for adolescents
- Early intervention for mental health issues
- Building strong family bonds and social support
- Community-based prevention programs
When to See a Doctor
- Inability to stop using a substance despite wanting to
- Substance use causing problems at work, school, or in relationships
- Physical withdrawal symptoms when stopping use
- Feeling that you need to use more of a substance to get the same effect
Frequently Asked Questions
Related Conditions
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