Manganese
A trace mineral essential for bone formation, carbohydrate metabolism, and antioxidant defense via manganese superoxide dismutase (MnSOD), an important mitochondrial antioxidant enzyme.
Known Health Benefits
Active Compounds
Manganese sulfate, manganese bisglycinate, manganese gluconate
Dosage Guidance
1.8–2.3 mg daily (RDA); 5–20 mg therapeutic
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
Neurological effects at very high environmental exposure; generally safe at dietary supplement doses
Known Drug Interactions
May interact with antacids, certain antibiotics, and iron supplements
Evidence Classification
Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.
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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.