InfectiousICD-10: B50-B54Around 249 million cases globally per year (WHO, 2022)
Malaria
Malaria is a life-threatening mosquito-borne disease caused by Plasmodium parasites transmitted through the bite of infected Anopheles mosquitoes. Symptoms typically appear 10–15 days after the infective bite and include high fever, chills, and flu-like illness. Without prompt treatment, severe malaria can lead to organ failure and death.
At a Glance
- Common symptoms
- High fever and chills, Profuse sweating, Headache
- Main treatments
- Artemisinin-based combination therapy (ACT), Chloroquine for P. vivax in sensitive areas, Intravenous artesunate for severe malaria
- Category
- Infectious · Around 249 million cases globally per year (WHO, 2022)
- See a doctor if
- Fever developing during or after travel to a malaria-endemic area
Symptoms
High fever and chills
Profuse sweating
Headache
Nausea and vomiting
Muscle and joint pain
Fatigue and malaise
Abdominal pain
Diarrhea
Anemia
Jaundice
Causes
- Plasmodium falciparum, P. vivax, P. ovale, or P. malariae parasites
- Bite from infected female Anopheles mosquito
- Blood transfusion from an infected donor
- Congenital transmission from mother to child
Risk Factors
- Travel to or residence in tropical and subtropical regions
- Lack of access to insecticide-treated bed nets
- Young children and pregnant women
- Weakened or absent immunity to malaria
- Lack of preventive antimalarial medication
Diagnosis
- Rapid diagnostic test (RDT) for malaria antigens
- Microscopic examination of blood smear
- Polymerase chain reaction (PCR) testing
- Complete blood count showing anemia and thrombocytopenia
Treatment
- Artemisinin-based combination therapy (ACT)
- Chloroquine for P. vivax in sensitive areas
- Intravenous artesunate for severe malaria
- Supportive care including IV fluids and antipyretics
- Primaquine to prevent relapse of P. vivax and P. ovale
Prevention
- Use insecticide-treated mosquito nets while sleeping
- Apply DEET-based insect repellent to exposed skin
- Take prophylactic antimalarial medication when traveling
- Wear long sleeves and pants during dusk and dawn
- Support indoor residual spraying programs
When to See a Doctor
- Fever developing during or after travel to a malaria-endemic area
- Cyclical fevers with severe chills and sweating
- Signs of confusion, seizures, or difficulty breathing
- Dark or reduced urine output suggesting kidney involvement
Frequently Asked Questions
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