MetabolicICD-10: D64.9Affects approximately 1.6 billion people worldwide — the most common blood disorder

Anemia

Also known as: Low Blood Count, Iron-Poor Blood, Low Hemoglobin, Low Iron, Anaemia

Anemia is a condition in which the blood lacks enough healthy red blood cells or hemoglobin to carry adequate oxygen to the body's tissues. It is the most common blood disorder in the world. Anemia can develop in three main ways — through blood loss, decreased red blood cell production, or increased red blood cell destruction — and it has many subtypes, the most frequent being iron-deficiency anemia, followed by vitamin B12 and folate deficiency anemias, anemia of chronic disease, and inherited forms such as sickle cell anemia and thalassemia. Symptoms range from mild, easily overlooked fatigue to severe complications affecting the heart, and treatment depends entirely on identifying and addressing the underlying cause.

At a Glance

Common symptoms
Fatigue and weakness, Pale or yellowish skin, Shortness of breath
Main treatments
Iron supplements (ferrous sulfate) for iron-deficiency anemia, Vitamin B12 injections or oral supplements, Folic acid supplementation
Category
Metabolic · Affects approximately 1.6 billion people worldwide — the most common blood disorder
See a doctor if
You experience persistent fatigue, weakness, or shortness of breath

Symptoms

Fatigue and weakness
Pale or yellowish skin
Shortness of breath
Dizziness or lightheadedness
Cold hands and feet
Rapid or irregular heartbeat
Headaches
Chest pain
Brittle nails

Causes

  • Iron deficiency (most common cause worldwide)
  • Vitamin B12 or folate deficiency
  • Chronic disease (kidney disease, cancer, inflammatory disorders)
  • Blood loss from heavy menstruation, ulcers, or injury
  • Bone marrow disorders (aplastic anemia, leukemia)
  • Hemolytic conditions that destroy red blood cells

Risk Factors

  • Women of reproductive age (due to menstrual blood loss)
  • Pregnancy without adequate iron supplementation
  • Poor diet lacking iron, B12, or folate
  • Chronic diseases such as kidney disease or cancer
  • Family history of inherited anemias (sickle cell, thalassemia)

Diagnosis

  • Complete blood count (CBC) to measure hemoglobin and hematocrit
  • Peripheral blood smear to examine red blood cell shape and size
  • Iron studies (serum ferritin, transferrin saturation)
  • Vitamin B12 and folate levels
  • Reticulocyte count to assess bone marrow response

Treatment

  • Iron supplements (ferrous sulfate) for iron-deficiency anemia
  • Vitamin B12 injections or oral supplements
  • Folic acid supplementation
  • Treatment of underlying chronic disease
  • Blood transfusions for severe anemia
  • Erythropoiesis-stimulating agents for kidney disease-related anemia

Prevention

  • Eat a diet rich in iron (lean meats, beans, spinach, fortified cereals)
  • Include vitamin C-rich foods to enhance iron absorption
  • Take prenatal vitamins during pregnancy
  • Get regular health screenings if at risk

When to See a Doctor

  • You experience persistent fatigue, weakness, or shortness of breath
  • Your skin appears unusually pale or you feel dizzy frequently
  • You have heavy menstrual periods or notice blood in your stool
  • You are pregnant and have not been screened for anemia

Frequently Asked Questions

Related Conditions

Related from the Supplement Library

These supplements have been studied in relation to Anemia. Always consult your healthcare provider before starting any supplement, especially if you take medications.

Related Reading

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