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CompoundModerate Evidence

Citicoline (CDP-Choline)

A neuroprotective compound providing both choline and cytidine (which converts to uridine), supporting acetylcholine and phosphatidylcholine synthesis for comprehensive brain health.

Known Health Benefits

Cognitive function and focus enhancement
Neuroprotection and brain repair support
Choline and uridine for brain membrane health
May support recovery from brain injury

Active Compounds

Cytidine 5'-diphosphocholine (CDP-choline)

Dosage Guidance

250–1000 mg daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Generally well tolerated; headache, GI upset rare

Known Drug Interactions

May interact with levodopa and anticholinergic drugs

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.