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CompoundModerate Evidence

Alpha-GPC

Alpha-glycerophosphocholine

The most bioavailable choline donor for the brain, rapidly raising acetylcholine levels for focus, memory, and cognitive performance. Also studied for HGH release and athletic performance.

Known Health Benefits

Acetylcholine precursor for focus and memory
Cognitive performance enhancement
Memory support and neuroprotection
May support HGH release with exercise

Active Compounds

L-Alpha glycerylphosphorylcholine

Dosage Guidance

300–600 mg daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Headache (if choline-sensitive), heartburn, dizziness at high doses

Known Drug Interactions

May interact with anticholinergic medications and scopolamine

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.