VitaminModerate Evidence

Pantothenic Acid (Vitamin B5)

Vitamin B5

Essential for CoA synthesis, adrenal hormone production, and fatty acid metabolism. Used therapeutically for adrenal fatigue support and acne (D-panthenol topically and internally).

Known Health Benefits

Adrenal hormone support (cortisol synthesis)

Acne management and skin health (D-panthenol)

Energy metabolism via acetyl-CoA

Wound healing support

Active Compounds

Pantothenic acid, panthenol, pantethine

Dosage Guidance

5–10 mg RDA; 500–2000 mg therapeutic for adrenal/acne

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Very safe; mild GI upset at very high doses (>10g)

Known Drug Interactions

Minimal known interactions

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.