Thiamine (Vitamin B1)
Vitamin B1
The first discovered B vitamin, essential for carbohydrate metabolism, nerve function, and energy production. Deficiency causes beriberi and is common in alcoholism and bariatric surgery.
Known Health Benefits
Active Compounds
Thiamine pyrophosphate (TPP), thiamine monophosphate
Dosage Guidance
1.2–3 mg/day standard; high-dose TTFD form used for fatigue/brain fog protocols
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
Generally very safe orally; IV forms may rarely cause anaphylaxis
Known Drug Interactions
May interact with diuretics, antacids, and alcohol (which severely depletes thiamine)
Evidence Classification
Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.
Related Entries
Have questions about Thiamine (Vitamin B1)?
Ask Mother Nature AI about dosing, interactions with your medications, whether it fits your health goals, and more — personalized to your health profile.
This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.