Riboflavin (Vitamin B2)
Vitamin B2
An essential coenzyme for energy production and antioxidant function. High-dose riboflavin (400 mg/day) has RCT evidence for migraine prevention and is recommended in clinical guidelines.
Known Health Benefits
Active Compounds
Riboflavin, FMN (flavin mononucleotide), FAD
Dosage Guidance
400 mg daily for migraine prevention (standard RDA: 1.3 mg)
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
Bright yellow-orange urine; generally very safe
Known Drug Interactions
May interact with phenobarbital, tricyclic antidepressants, and doxorubicin
Evidence Classification
Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.
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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.