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ReproductiveICD-10: N80Affects approximately 1 in 10 women of reproductive age worldwide

Endometriosis

Also known as: Endo

Endometriosis is a chronic condition in which tissue similar to the uterine lining grows outside the uterus, commonly on the ovaries, fallopian tubes, and pelvic tissues. It causes inflammation, pain, and scar tissue formation, and is a leading cause of infertility in women. Diagnosis is often delayed by an average of 7 to 10 years.

Symptoms

Severe menstrual cramps (dysmenorrhea)
Chronic pelvic pain between periods
Pain during or after sexual intercourse
Heavy or irregular menstrual bleeding
Pain with bowel movements or urination during menstruation
Bloating, nausea, or diarrhea during periods
Fatigue and exhaustion
Difficulty getting pregnant

Causes

  • Retrograde menstruation (menstrual blood flowing backward into the pelvis)
  • Immune system dysfunction failing to clear misplaced tissue
  • Hormonal factors, particularly estrogen dominance
  • Genetic predisposition
  • Possible coelomic metaplasia

Risk Factors

  • Family history of endometriosis
  • Early onset of menstruation (before age 11)
  • Short menstrual cycles (less than 27 days)
  • Never having given birth
  • Low body mass index

Diagnosis

  • Pelvic examination to check for cysts or scars
  • Transvaginal ultrasound to visualize endometriomas
  • MRI for detailed imaging of deep endometriosis
  • Laparoscopy (surgical visualization) for definitive diagnosis

Treatment

  • NSAIDs for pain management
  • Hormonal therapies including birth control pills and GnRH agonists
  • Progestin therapy (IUD, injections, or pills)
  • Laparoscopic excision surgery to remove endometrial implants
  • Hysterectomy with oophorectomy in severe, refractory cases
  • Fertility treatments such as IVF for those trying to conceive

Prevention

  • There is no known way to prevent endometriosis
  • Hormonal contraceptives may reduce the risk of progression
  • Regular exercise and anti-inflammatory diet may help manage symptoms

When to See a Doctor

  • Menstrual pain is severe enough to interfere with daily activities
  • You are having difficulty getting pregnant
  • You experience chronic pelvic pain outside your menstrual period
  • Pain during intercourse is persistent or worsening

Frequently Asked Questions

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