Alpha-Lipoic Acid (ALA)
A unique universal antioxidant that functions in both fat-soluble and water-soluble environments, regenerating other antioxidants. One of the most evidence-backed supplements for diabetic neuropathy.
Known Health Benefits
Active Compounds
R-alpha-lipoic acid (R-ALA), S-alpha-lipoic acid, dihydrolipoic acid (DHLA)
Dosage Guidance
300–600 mg R-ALA daily (take on empty stomach)
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
Nausea, GI upset; may significantly lower blood sugar — monitor if diabetic
Known Drug Interactions
May significantly enhance insulin and diabetes medications; may interact with thyroid medications
Evidence Classification
Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.
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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.