L-Citrulline
An amino acid that converts to arginine in the kidney more efficiently than arginine itself, increasing nitric oxide production. Studied for cardiovascular health and exercise performance.
Known Health Benefits
Active Compounds
L-citrulline, citrulline malate
Dosage Guidance
3–6 g L-citrulline or 6–8 g citrulline malate pre-exercise
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
Generally well tolerated; mild GI effects at high doses
Known Drug Interactions
May interact with blood pressure medications and nitrate drugs (e.g., sildenafil)
Evidence Classification
Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.
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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.