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Mother Nature AI
CompoundModerate Evidence

D-Mannose

A simple sugar that prevents E. coli from adhering to the urinary tract lining, studied as an effective non-antibiotic intervention for UTI prevention and treatment.

Known Health Benefits

UTI prevention via E. coli adhesion inhibition
May shorten UTI duration
Microbiome-neutral alternative to antibiotics
Safe for diabetics (minimal blood sugar impact)

Active Compounds

D-mannose

Dosage Guidance

500–2000 mg daily for prevention; 1500 mg every 2–3 hours during active UTI

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Loose stools at high doses; generally very safe

Known Drug Interactions

Minimal known interactions

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

Probiotics (Lactobacillus) L-Glutamine Vitamin C

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.