Skip to main content
CompoundModerate Evidence

DHEA (Dehydroepiandrosterone)

The most abundant steroid hormone precursor in the body, peaking in early adulthood and declining with age. Studied for vitality, bone density, immune function, and adrenal insufficiency.

Known Health Benefits

Hormone precursor (testosterone and estrogen)
Age-related vitality and energy support
Bone density maintenance
Immune modulation

Active Compounds

Dehydroepiandrosterone, DHEA-S (sulfated form)

Dosage Guidance

25–100 mg daily — only use with serum DHEA-S testing and physician guidance

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Hormonal side effects (acne, hair loss, voice changes); not recommended without lab testing

Known Drug Interactions

Interacts with hormone therapies, anticoagulants, insulin, and triazolam

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

Have questions about DHEA (Dehydroepiandrosterone)?

Ask Mother Nature AI about dosing, interactions with your medications, whether it fits your health goals, and more — personalized to your health profile.

This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.