Milk Thistle
Silybum marianum
Primarily studied for liver-protective effects, milk thistle contains silymarin which supports hepatocyte regeneration and is one of the most evidence-backed herbs for liver health.
Known Health Benefits
Active Compounds
Silymarin, silibinin, silydianin, silichristin
Potential Side Effects
Mild GI effects; rare allergic reactions (ragweed family)
Known Drug Interactions
May affect CYP2C9 and CYP3A4 substrates including statins
Evidence Classification
Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.
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