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HerbModerate Evidence

Artichoke Leaf Extract

Cynara cardunculus var. scolymus

A bitter herb with clinical evidence for liver health, LDL cholesterol reduction, and digestive support through choleretic and hepatoprotective mechanisms.

Known Health Benefits

Liver health and detoxification support
LDL cholesterol reduction
Digestive bitter tonic
Antioxidant protection

Active Compounds

Cynarin, chlorogenic acid, luteolin, apigenin, caffeic acid

Dosage Guidance

640–1800 mg extract daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

GI upset; allergic reactions possible (ragweed family); contraindicated in bile duct obstruction

Known Drug Interactions

May interact with statins and bile acid sequestrants

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.