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CompoundModerate Evidence

Quercetin

A ubiquitous flavonoid antioxidant found in apples, onions, and capers with potent anti-inflammatory effects, antihistamine properties, and emerging research as a potential senolytic agent.

Known Health Benefits

Anti-inflammatory (NF-κB, COX-2 inhibition)
Natural antihistamine for allergies
Cardiovascular protection
Senolytic potential (emerging research)

Active Compounds

Quercetin aglycone, quercetin dihydrate, quercetin phytosome

Dosage Guidance

500–1000 mg daily (with bromelain for absorption)

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Generally well tolerated; headache, GI upset at high doses; take with food

Known Drug Interactions

May interact with blood thinners, chemotherapy, and CYP3A4/P-glycoprotein substrates

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.