Vitamin B6
Pyridoxine
Critical for neurotransmitter synthesis, amino acid metabolism, and immune function. P5P (pyridoxal-5-phosphate) is the active form. Deficiency contributes to depression, PMS, and cognitive decline.
Known Health Benefits
Active Compounds
Pyridoxal 5'-phosphate (P5P), pyridoxine, pyridoxamine
Potential Side Effects
Peripheral neuropathy with prolonged use >200 mg/day; nausea at high doses
Known Drug Interactions
May interact with levodopa, phenytoin, and cycloserine
Evidence Classification
Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.
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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.