DermatologicalICD-10: R61Affects an estimated 3% of the population

Hyperhidrosis

Also known as: Excessive sweating, Sweaty palms, Overactive sweat glands

Hyperhidrosis is excessive sweating beyond what the body needs to regulate temperature. It commonly affects the palms, soles, underarms, and face, and can occur even when a person is cool or at rest. Primary hyperhidrosis has no underlying medical cause and often runs in families, while secondary hyperhidrosis results from another condition or medication. Though not dangerous, it can be socially and emotionally distressing, and effective treatments are available.

Symptoms

Visible, excessive sweating unrelated to heat or exertion
Sweaty, clammy palms and soles
Soaked clothing from underarm sweating
Sweat that interferes with daily tasks (gripping, writing, using devices)
Skin problems such as maceration or fungal infections from constant moisture

Causes

  • Overactivity of the sweat glands' nerve signals (primary hyperhidrosis)
  • Genetics and family history
  • Underlying conditions (thyroid disease, diabetes, menopause, infections)
  • Certain medications
  • Anxiety and stress (which can amplify it)

Risk Factors

  • Family history of excessive sweating
  • Onset in childhood or adolescence (primary type)
  • Thyroid or metabolic conditions (secondary type)
  • Certain medications

Diagnosis

  • Clinical evaluation of sweating pattern and triggers
  • Starch-iodine test to map affected areas
  • Blood tests to rule out thyroid or other underlying causes
  • Distinguishing primary (localized, symmetric) from secondary (generalized) sweating

Treatment

  • Clinical-strength or prescription antiperspirants (aluminum chloride)
  • Iontophoresis for hands and feet
  • Botulinum toxin (Botox) injections for underarms, palms, or soles
  • Oral anticholinergic medications
  • Topical glycopyrronium wipes
  • Microwave or surgical options (including sympathectomy) for severe cases

Prevention

  • Hyperhidrosis can't always be prevented, but triggers can be reduced
  • Wear breathable, moisture-wicking fabrics
  • Use absorbent foot powders and change socks regularly
  • Manage stress and anxiety
  • Avoid known dietary triggers like spicy food and caffeine

When to See a Doctor

  • Sweating disrupts your daily activities or emotional well-being
  • You suddenly start sweating excessively without explanation
  • Sweating occurs mainly at night or all over the body (possible underlying cause)
  • Sweating is accompanied by weight loss, fever, or a racing heart

Frequently Asked Questions

Related Conditions

Hyperthyroidism

Endocrine

Menopause

Reproductive

Anxiety Disorders

Mental Health

Athlete's Foot

Dermatological

Related from the Supplement Library

Sage

Moderate

Herb · Reduces menopausal hot flashes and night sweats

Magnesium Glycinate

Strong

Mineral · Improves sleep quality and onset

These supplements have been studied in relation to Hyperhidrosis. Always consult your healthcare provider before starting any supplement, especially if you take medications.

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