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Amino AcidPreliminary Evidence

GABA (Gamma-Aminobutyric Acid)

The primary inhibitory neurotransmitter in the brain. Oral supplementation studies show modest but meaningful effects on anxiety and sleep, with the natural PharmaGABA form showing better CNS effects.

Known Health Benefits

May reduce anxiety and stress
Sleep onset support
Relaxation promotion
May support HGH release with exercise

Active Compounds

Gamma-aminobutyric acid, PharmaGABA (natural fermentation form)

Dosage Guidance

100–750 mg daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Generally well tolerated; tingling, numbness, and drowsiness reported at high doses

Known Drug Interactions

May enhance effects of CNS depressants, benzodiazepines, and anticonvulsants

Evidence Classification

Preliminary Evidence

Based on in vitro studies, animal models, pilot trials, or traditional use documentation. Clinical evidence is limited.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.