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HerbModerate Evidence

Passionflower

Passiflora incarnata

A calming vine herb with clinical evidence for anxiety relief comparable to low-dose benzodiazepines, acting primarily on GABA-A receptors without dependency concerns.

Known Health Benefits

Reduces anxiety and nervous tension
Promotes sleep onset
May reduce nervous restlessness
Mild sedative properties

Active Compounds

Chrysin, vitexin, isovitexin, orientin, harmane alkaloids

Dosage Guidance

400–900 mg standardized extract daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Drowsiness, dizziness; use caution when driving

Known Drug Interactions

May enhance sedatives, benzodiazepines, and MAOIs

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.