Kava
Piper methysticum
A Pacific island herb with strong clinical evidence for anxiety relief, with multiple meta-analyses showing significant anxiolytic effects comparable to benzodiazepines without cognitive impairment.
Known Health Benefits
Active Compounds
Kavalactones (kavain, dihydrokavain, methysticin, yangonin)
Dosage Guidance
70–250 mg kavalactones daily; cycle use (not continuous)
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
Liver concerns with heavy, prolonged use; dermopathy with chronic high-dose; drowsiness
Known Drug Interactions
MAJOR interactions with alcohol, benzodiazepines, and hepatotoxic drugs
Evidence Classification
Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.
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