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ProbioticStrong Evidence

Saccharomyces boulardii

A beneficial probiotic yeast (not a bacteria) that is naturally antibiotic-resistant — making it uniquely effective for antibiotic-associated diarrhea and C. difficile prevention.

Known Health Benefits

Prevents antibiotic-associated diarrhea
C. difficile prevention and recurrence reduction
Traveler's diarrhea support
Gut microbiome restoration post-antibiotics

Active Compounds

Saccharomyces cerevisiae var. boulardii (live yeast)

Dosage Guidance

250–500 mg (5–10 billion CFU) daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Gas, bloating; contraindicated in immunocompromised patients (fungal infection risk)

Known Drug Interactions

Not affected by antibiotics (unlike bacterial probiotics); antifungals will eliminate it

Evidence Classification

Strong Evidence

Supported by randomized controlled trials (RCTs), systematic reviews, or meta-analyses published in peer-reviewed journals.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.