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MushroomModerate Evidence

Turkey Tail

Trametes versicolor

Rich in polysaccharopeptides PSP and PSK, turkey tail is the most evidence-backed medicinal mushroom for immune support, with approved clinical use in Japan's cancer treatment protocols.

Known Health Benefits

Immune support (PSP and PSK beta-glucans)
Oncology adjunct support (used in Japan)
Prebiotic effects for gut microbiome
Antioxidant activity

Active Compounds

Polysaccharide-K (PSK/krestin), polysaccharopeptide (PSP), beta-glucans

Potential Side Effects

Mild GI effects; darkened stools; not for autoimmune conditions without guidance

Known Drug Interactions

May interact with immunosuppressants and chemotherapy — consult oncologist

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.