Skip to main content
MineralModerate Evidence

Magnesium L-Threonate

A novel form of magnesium developed at MIT that uniquely crosses the blood-brain barrier, studied for cognitive enhancement, memory improvement, and neuroprotection.

Known Health Benefits

Crosses the blood-brain barrier
Cognitive enhancement and memory
May support neuroplasticity and synapse density
Sleep quality improvement

Active Compounds

Elemental magnesium, L-threonate

Dosage Guidance

1.5–2 g threonate form daily (delivering ~144 mg elemental magnesium)

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Mild GI effects initially; headache in some users

Known Drug Interactions

Similar to other magnesium forms

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

Have questions about Magnesium L-Threonate?

Ask Mother Nature AI about dosing, interactions with your medications, whether it fits your health goals, and more — personalized to your health profile.

This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.