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MineralModerate Evidence

Selenium

Trace mineral essential for thyroid hormone activation, antioxidant defense via glutathione peroxidase enzymes, and immune health. Research supports use in Hashimoto's thyroiditis.

Known Health Benefits

Thyroid hormone metabolism (T4 to T3 conversion)
Antioxidant defense (glutathione peroxidase)
Immune support
May support fertility in both sexes

Active Compounds

Selenomethionine, sodium selenite, selenocysteine

Dosage Guidance

55–200 mcg daily (selenomethionine form preferred)

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Garlic breath, hair loss, nail brittleness, and neuropathy at high doses (selenosis)

Known Drug Interactions

May interact with chemotherapy drugs, statins, and blood thinners

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.