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HerbModerate Evidence

Black Cohosh

Actaea racemosa

The most studied and evidence-backed herb for menopausal symptom relief, with clinical trials supporting significant reduction in hot flashes, night sweats, and mood disturbances.

Known Health Benefits

Reduces menopausal hot flashes
Improves night sweats
Mood and anxiety support during menopause
May improve sleep in perimenopause

Active Compounds

Triterpene glycosides (actein, cimicifugoside), caffeic acid derivatives

Dosage Guidance

20–40 mg standardized extract twice daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

GI upset, headache; rare liver concerns — discontinue if jaundice or dark urine develops

Known Drug Interactions

May interact with hormone therapies, tamoxifen, and hepatotoxic drugs

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.