Skip to main content
Fatty AcidModerate Evidence

Evening Primrose Oil

The richest non-pharmaceutical source of gamma-linolenic acid (GLA), studied for hormonal balance, PMS symptoms, breast pain, and inflammatory skin conditions like eczema.

Known Health Benefits

GLA source for anti-inflammatory prostaglandins
PMS and cyclical breast pain relief
Menopausal symptom support
Eczema and inflammatory skin support

Active Compounds

Gamma-linolenic acid (GLA), linoleic acid

Dosage Guidance

500–3000 mg daily

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

May increase bleeding risk; headache, GI upset; not recommended with seizure risk

Known Drug Interactions

May interact with blood thinners, phenothiazines, and blood pressure medications

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

Have questions about Evening Primrose Oil?

Ask Mother Nature AI about dosing, interactions with your medications, whether it fits your health goals, and more — personalized to your health profile.

This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.