Sodium Butyrate
A short-chain fatty acid that serves as the primary energy source for colon cells, with potent effects on gut barrier integrity, inflammation, and epigenetic regulation via HDAC inhibition.
Known Health Benefits
Active Compounds
Sodium butyrate, tributyrin, calcium-magnesium butyrate
Dosage Guidance
600–3000 mg daily (enteric-coated preferred)
Always consult a healthcare provider for personalized dosing.
Potential Side Effects
GI discomfort; sulfur-like smell (enteric-coated mitigates this)
Known Drug Interactions
Minimal known interactions; may enhance some chemotherapy effects
Evidence Classification
Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.
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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.