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HerbModerate Evidence

Licorice Root (DGL)

Glycyrrhiza glabra

A widely used herb for digestive healing and adrenal support. DGL (deglycyrrhizinated) form removes the component that raises blood pressure, making it safe for gut-healing protocols.

Known Health Benefits

Gut lining support and mucosal healing (DGL)
Adrenal support and cortisol modulation
Anti-inflammatory and antiviral
Expectorant for respiratory conditions

Active Compounds

Glycyrrhizin, glabridin, liquiritigenin, chalcones, flavonoids

Dosage Guidance

DGL: 400–3000 mg chewable tablets before meals

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Non-DGL form: may raise blood pressure, lower potassium; DGL form is much safer for most users

Known Drug Interactions

Non-DGL: interacts with diuretics, antihypertensives, and corticosteroids

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.