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ProbioticModerate Evidence

Probiotics (Bifidobacterium)

Bifidobacterium species are among the most clinically studied probiotic strains, dominant in infants and critical throughout life for gut health, immunity, and mental health via the gut-brain axis.

Known Health Benefits

Gut microbiome diversity and health
Immune system modulation
Constipation relief
Mental health support via gut-brain axis (B. longum)

Active Compounds

Bifidobacterium longum, B. breve, B. infantis, B. lactis, B. bifidum

Dosage Guidance

5–100 billion CFU daily depending on strain and indication

Always consult a healthcare provider for personalized dosing.

Potential Side Effects

Temporary bloating and gas during initial use

Known Drug Interactions

May reduce effectiveness if taken simultaneously with antibiotics — separate by 2+ hours

Evidence Classification

Moderate Evidence

Supported by cohort studies, case-control studies, or multiple observational studies with consistent findings.

Related Entries

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This entry is for educational purposes only. It is not medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any supplement regimen, especially if you take medications or have health conditions.